Patients requiring arthroscopic shoulder surgery Rebound pain, Interscalene brachial plexus block, Dexmedetomidine, Post operative pain, Arthroscopic shoulder surgery.
Conditions
Interventions
The experimental group will receive ropivacaine combined with dexmedetomidine at a dose of 1 mcg/kg based on ideal body weight, with a maximum dose not exceeding 75 mcg, for interscalene brachial plex
Experimental Drug,Active Comparator Drug
Dexmedetomidine combined with ropivacaine ,Ropivacaine
Sponsors
Ratchadapisek Research Funds
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Elective arthroscopic shoulder surgery (Arthroscopic rotator cuff repair, Bankart repair, SLAP or labrum surgery, adhesive capsulitis or acromioclavicular joint surgery) 2. Patients aged 18-75 years old 3. ASA physical status classification 1-3
Exclusion criteria
Exclusion criteria: 1. Coagulation disorders 2. Neuropathic disorders 3. Diaphragmatic paralysis 4. Severe cardiopulmonary disease 5. Systemic steroid use 6. Uncontrolled diabetes 7. Psychiatric disorders 8. Pregnancy 9. Severe obesity BMI>35kg/m2 10. Asthma or chronic obstructive pulmonary disease 11. A history of surgery or radiation therapy in the cervical region adjacent to the interscalene block site
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of rebound pain following the wear-off of local anesthetic effect Numeric pain rating scale greater than or equal to 7 | — |
Secondary
| Measure | Time frame |
|---|---|
| Rebound pain score within 12 hours after the anesthetic effect has worn off subtracting the lowest pain score before the anesthetic effect wears off from the highest pain score within 12 hours after the anesthetic effect has worn off,Onset of rebound pain Once the interscalene brachial plexus block is done Duration,Duration of rebound pain Duration from the onset of rebound pain Duration,Duration of sensory blockade From the time of interscalene brachial plexus block to resolution of sensory blockade Duration,Duration of motor blockade From the time of interscalene brachial plexus block to resolution of motor blockade Duration,Time to first analgesia From the time of interscalene brachial plexus block to the first analgesic request Duration,Morphine consumption During hospitalization in post operative period Milligram,Volatile agent consumption During surgery millilitre,Emergence time From discontinue of inhalation anesthetics to state full name on command Duration ,Richmon agitation sedation score within 24 hours after surgery Richmon agitation sedation score,Length of hospital stay After surgery Days,Adverse events After surgery Number of events including hypotension, bradycardia, desaturation, nausea and vomiting,Satisfaction scores within 7 days after surgery Numeric rating scale (-5 to 5)) | — |
Countries
Thailand
Contacts
Public ContactPongkwan Jinaworn
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed