auricular keloids Auricular keloid Intralesional corticosteroid injection Keloid recurrence Steroid softening
Conditions
Interventions
Patients in the intervention group receive serial intralesional injections of Triamcinolone acetonide (40 mg/ml) every 4 weeks prior to surgery x 3 times. Surgical excision is then performed approxima
Experimental Drug,Active Comparator Procedure/Surgery
Intervention group- Serial Preoperative Intralesional Steroid Injections (Preoperative steroid injection+ Excision+ Postoperative steroid injection),Control group (Excision+ Postoperative steroid inje
Sponsors
Buriram Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 years or older. 2. Patients who have been diagnosed with an auricular keloid by a plastic surgeon. 3. Patients who are willing to participate and are able to follow up according to the study's schedule.
Exclusion criteria
Exclusion criteria: 1. Patients under 18 years of age. 2. Patients who have previously received treatment for the keloid at the study site but have not shown a satisfactory response to the treatment. 3. Patients who have a history of a chronic or autoimmune disease, as well as those who are immunocompromised. 4. Patients who have received radiotherapy in the area of the keloid. 5. Patients who are pregnant or breastfeeding. 6. Patients who do not consent to participate in the study. 7. Patients who cannot be followed up according to the study's schedule.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Keloid recurrence rate All participants will be followed up monthly for a total of 12 months after the surgery By physical examination | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound Complications: wound dehiscence, wound infection Every month for a total of 12 months after the surgery By physical examination,Intralesional steroid injection complication: Skin atrophy, Telangiectasia, Infection, Skin necrosis Every month after steroid injection and then monthly for a total of 12 months after the surgery By physical examination | — |
Countries
Thailand
Contacts
Public ContactPremsak Sakarinpanichakul
Buriram Hospital
Outcome results
None listed