Adult critically-ill patients who require CRRT using regional citrate anticoagulation (RCA) continuous renal replacement therapy regional citrate anticoagulation filter lifespan dialysis efficiency sieving coefficient
Conditions
Interventions
Intervention: Prolonged use of the same CRRT circuit with RCA beyond 72 hours.
Duration: Up to 96 to 120 hours.
Monitoring: Patients are followed for filter efficacy using the sieving coefficient (FUN
Prolonged use of the same CRRT circuit with RCA beyond 72 hours.
Sponsors
Routine to Research Siriraj
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Adult (>= 18 year-old) critically-ill patients 2. require CRRT using regional citrate anticoagulation (RCA) for at least 72 hours
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to the use of citrate in continuous renal replacement therapy 2. Patients who develop new contraindications or are at increased risk for complications from citrate use during the course of continuous renal replacement therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| efficacy of extending CRRT 96-120 hours sieving coefficient | — |
Secondary
| Measure | Time frame |
|---|---|
| safety outcomes 96-120 hours e.g. electrolyte imbalance, bleeding, and mortality. | — |
Countries
Thailand
Contacts
Public ContactChinnapat Sriboonyaket
Faculty of Medicine, Siriraj Hospital
Outcome results
None listed