Does ondansetron can reduce incidence of oculocardiac reflex Ondansetron, Bradycardia, Oculocardiac reflex, OCR, Pediatric strabismus surgery, Pediatric anesthesia
Conditions
Interventions
Ondansetron preoperation,No preoperative ondansetron
Experimental Drug,No Intervention No treatment
Ondansetron,No treatment
Sponsors
Pediatric fellow ship program at Queen Sirikit National Institute of Child Health
Eligibility
Sex/Gender
All
Age
1 Years to 12 Years
Inclusion criteria
Inclusion criteria: Children aged 1-12 years undergoing strabismus surgery under general anesthesia ASA physical status 1-2
Exclusion criteria
Exclusion criteria: 1.History of allergy to ondansetron. 2.Undergoing other types of surgery in addition to strabismus surgery. 3.Presence of other current ocular diseases such as keratitis or glaucoma (patients with a past history of these conditions that have completely resolved may be eligible). 4.Previous ocular surgery. 5.History of cardiovascular or neurological disorders, including: Congenital heart disease Cardiac arrhythmias (including bradycardia and QT prolongation) Epilepsy Central nervous system infections Traumatic brain injury Liver cirrhosis or hepatitis Asthma Down syndrome 6. Current use of the following medications: drugs: sodium valproate, carbamazepine, lamotrigine, levetiracetam, oxcarbazepine, ethosuximide, topiramate drugs: atenolol, bisoprolol, metoprolol Glaucoma medications: timolol Selective serotonin reuptake inhibitors (SSRIs): fluoxetine, fluvoxamine, sertraline Bronchodilator inhalers: salbutamol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence oculocardiac reflex intraoperative period incidence | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence postoperative nausea vomitting post operative period incidence | — |
Countries
Thailand
Contacts
Public Contactvarunya sermkasemsin
Queen Sirikit National Institute of Child Health
Outcome results
None listed