efficacy of Intra-articular Hyaluronic acids injections in ankle osteoarthritis ankle osteoarthritis, hyaluronic acid
Conditions
Interventions
1.Paticipant in this group will receive Hyaluronic acid injection at effected ankle joint 3 doses with 1 week interval.
2.All participants will receive injection by Assoc. Prof. Marut Arunakul, M.D. u
Active Comparator Drug,Active Comparator Drug
weekly,Monthly
Sponsors
Thammasat University Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients agree to participate in the study 2.Age above 18 years old 3.No condition of bed bound or bed ridden 4.Diagnosed with osteoarhtritis of ankle by Assoc. Prof. Marut Arunakul, M.D. Must be in stage 2 or 3a or 3b of Takakura-Tanaka classification
Exclusion criteria
Exclusion criteria: 1.History of steroid injection at the ankle 2.History of septic ankle 3.Skin infection around injection site before entering the study 4.Hypersensitivities to avian protein or any components of hyaluronan-based injection 5.Osteochondral lesion of the talus 6.History of Gout nad others inflammatory joint
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Function pre injection, and 1 month, 3 months, 6 months, 9 months, 12 months after injection Thai version of foot and ankle ability score | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain pre injection, and 1 month, 3 months, 6 months, 9 months, 12 months after injection Visual analog scale | — |
Countries
Thailand
Contacts
Public ContactWarisara Lertcheewanan
Faculty of Medicine, Thammasat University
Outcome results
None listed