Healthy participants Ulva rigida, postprandial dysmetabolism, seaweed, appetite, carbohydrate digestion
Conditions
Interventions
A high-carbohydrate, moderate-fat meal. The caloric distribution was approximately 60% carbohydrate, 30% fat and 10% protein.,A high-carbohydrate, moderate-fat meal plus 5 g dry weight of U. rigida.
Control,Seaweed meal
Sponsors
Mahidol University (Fundamental Fund: fiscal year 2025 by National Science Research and Innovation Fund (NSRF))
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Male and female aged 20-50 years old 2. BMI 18.5-23 kg/m2 3. Fasting blood glucose less than 100 mg/dL 4. Fasting blood triglyceride less than 150 mg/dL 5. Blood urea nitrogen (BUN) 8-24 mg/dL 6. Creatinine 0.84 - 1.21 mg/dL 7. Aspartate transaminase (AST) 8 - 48 U/L 8. Alanine transaminase (ALT) 7 - 55 U/L 9. Blood pressure less than 120/80 mmHg 10. No smoker and alcohol users
Exclusion criteria
Exclusion criteria: 1. Chronic diseases such as diabetes mellitus, hypercholesterolemia, liver and kidney diseases etc. 2. Using any dietary supplements or medications related to dietary fibers and antioxidants 3. Breastfeeding, pregnant or planning a pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postprandial blood glucose, insulin, triglyceride, free fatty acid 0-240 min Assay kits | — |
Secondary
| Measure | Time frame |
|---|---|
| Postprandial blood GLP-1, antioxidant capacity, inflammatory response 0-240 min Assay kits, chemical reactions,Serum shrort-chain fatty acids 240 min GC-MS,Appetite sensation 0-240 min Visual analog scale | — |
Countries
Thailand
Contacts
Public ContactThavaree Thilavech
Faculty of Pharmacy, Mahidol University
Outcome results
None listed