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Efficacy of light-emitting diodes therapy in reduction of postoperative swelling following orthognathic surgery: A double-blind randomized controlled trial

Efficacy of light-emitting diodes therapy in reduction of postoperative swelling following orthognathic surgery: A double-blind randomized controlled trial

Status
Unknown
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250818003
Enrollment
28
Registered
2025-08-18
Start date
2025-03-31
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative swelling following orthognathic surgery postoperative swelling orthognathic surgery

Interventions

LED therapy was applied using a wavelength of 625 nm. The LED probe had an irradiation area of 1,000 square centimeter with a power output of 60 mW, resulting in a power density of 0.06 mW per square
red LED,placebo

Sponsors

The Royal College of Dental Surgeons of Thailand
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1 Patients aged 18 to 40 years who provided informed consent to participate in the study, 2 Patients who underwent orthognathic surgery involving both the maxilla and mandible, using either conventional Le Fort I osteotomy or segmental Le Fort I osteotomy for the maxilla, and bilateral sagittal split osteotomy (BSSO) for the mandible. Additional procedures such as anterior subapical osteotomy or genioplasty may have been performed as part of the mandibular surgery. All surgeries were performed by faculty members of the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Prince of Songkla University, 3 Patients with no craniofacial anomalies, such as cleft lip and palate, 4 Participants had no prior history of facial trauma or any previous surgical procedures involving the face or jaws before enrollment in the study, 5 Patients were classified as ASA Physical Status Class I or II according to the American Society of Anesthesiologists (ASA) physical status classification system, 6 Patients with no psoriasis affecting the facial or cervical (neck) region, 7 Patients had no history of photosensitivity disorders or prior use of photosensitizing drugs

Exclusion criteria

Exclusion criteria: 1 Patients with surgical complications, including surgical site infection, bad split, or avascular necrosis, 2 Patients who developed allergic reactions to medications, causing facial rash and swelling postoperatively, 3 Patients with connective tissue inflammatory diseases such as systemic lupus erythematosus, rheumatoid arthritis, scleroderma, dermatomyositis, mixed connective tissue disease, and others

Design outcomes

Primary

MeasureTime frame
postoperative swelling at 3, 7,14,30 and 90 days postoperative 3D volume scan and linear measurement

Secondary

MeasureTime frame
postopeative pain at 3, 7,14,30 and 90 days postoperative visual analog scale

Countries

Thailand

Contacts

Public ContactAgkayuth Panuwattanakon

Faculty of Dentistry, Prince of Songkla University

agkayuth.p@psu.ac.th0816794217

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026