Uterine myoma, ovarian neoplasm, ovarian cyst, endometriosis, endometrial hyperplasia, uterine prolapse, and intra-abdominal adhesion Simethicone, Gynecologic laparoscopy, Bowel interference, Operative visual field, Preoperative preparation
Conditions
Interventions
Participants received oral simethicone 80 mg three times on the day before surgery at 12:00 pm, 6:00 pm, and 12:00 am.,Participants received standard preoperative care without administration of simeth
Simethicone,Placebo
Sponsors
Department Obstetrics and Gynecology, Police General Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Female patients aged 18 to 70 years undergoing gynecologic laparoscopic surgery at Police General Hospital, Bangkok, Thailand and diagnosed with one or more of the following conditions: Uterine myoma, Ovarian neoplasm ,Ovarian cyst, Endometriosis, Endometrial hyperplasia, Uterine prolapse, Intra-abdominal adhesion
Exclusion criteria
Exclusion criteria: Patients had a history of allergy to simethicone, or had contraindications for gynecologic laparoscopic surgery including pregnancy, coagulopathy, unstable vital signs, paralytic ileus, severe cardiac or pulmonary disease, retinal detachment, intra-abdominal infection and peritonitis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bowel interference At the time of intraoperative laparoscopic surgery Number of bowel interruption,Quality of surgical field visualization Immediately after creation of pneumoperitoneum and before initiation of the surgical procedure. Five-point scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of the rate of intraoperative and postoperative complications between patients who received simethicone and those who did not receive the drug Intraoperative laparoscopic surgery Medical record review and clinician documentation of intraoperative and postoperative complications | — |
Countries
Thailand
Contacts
Public ContactGotchaphan Noppornphan
Department of Obstetrics and Gynaecology, Police General Hospital
Outcome results
None listed