Comparison of standard dose protocol with extended dose protocol of letrozole for ovulation induction in women with PCOS

Status

Unknown

Phases

Phase 1Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250811004

Enrollment

174

Registered

2025-08-11

Start date

2025-03-28

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polycystic ovaries reproductive age females with anovulation PCOS anovulation letrozole

Interventions

Letrozole given for 5 days for ovulation induction in female with subfertility.,Letrozole given for 10 days for ovulation induction in female with subfertility.

Active Comparator Drug,Active Comparator Drug

Letrozole short course,Letrozole long course

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Women of 18-35 years of age. 2. Diagnosed case of PCOS on TVS. 3. Subfertility for one year or more.

Exclusion criteria

Exclusion criteria: 1. .Patients with evidence of tubal blockage on HSG/laparoscopy. 2. Patients whose husband has abnormal semen analysis 3. Patients with benign ovarian/uterine tumors. 4. Patients having other coexistent cause of infertility like endometriosis or fibroid 5. Patients with uncontrolled metabolic or endocrinological disorder

Design outcomes

Primary

Measure	Time frame
follicle development day 12 of cycle USG measurement of follicle on day 12	—

Secondary

Measure	Time frame
Clinically proven pregnancy at the end of cycle/missed period Serum beta HCG	—

Countries

Pakistan

Contacts

Public ContactRizwana Tariq

Fatima Jinnah Medical University

rizwanatariq@hotmail.com923236464820

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026