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Comparative study of the efficacy of fentanyl in anesthesia for morbid obesity patients undergoing Sleeve gastrectomy using different dosage calculations between 1 mcg/kg of body weight and 2 mcg/kg of body weight

Comparative study of the efficacy of fentanyl in anesthesia for morbid obesity patients undergoing Sleeve gastrectomy using different dosage calculations between 1 mcg/kg of body weight and 2 mcg/kg of body weight

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250811002
Enrollment
40
Registered
2025-08-11
Start date
2024-11-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Morbid obesity patients Laparoscopic sleeve gastrectomy Fentanyl dosage Morbid obesity, laparoscopic sleeve gastrectomy, fentanyl dose, general anesthesia

Interventions

Patients assigned to receive fentanyl 2 mcg per kg group were given intravenous bolus fentanyl 2 microgram per lean body weight during induction phase before intubation.,Patients assigned to receive f
Active Comparator Drug,Active Comparator Drug
fentanyl 2 mcg per kg group,fentanyl 1 mcg per kg group

Sponsors

Udon Thani Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. male or female patients with age of 18 years old or older and diagnosed with morbid obesity (body mass index more than 40, or 35 with obesity associated medical conditions such as diabetes, dyslipidemia and hypertension) 2. ASA class II-III 3. undergoing laparoscopic sleeve gastrectomy under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients who were blinded, illiterate and also not welling to participate in the study. 2. Patients with a history of using pain medications, including NSAIDs or opioids during the last 7 days prior the surgery and patients with any history of opioid allergy 3. Patients have psychiatric conditions.

Design outcomes

Primary

MeasureTime frame
pain at post anesthetic care unit visual analog scale,pain 24 hours after the operation visual analog scale

Secondary

MeasureTime frame
heart rate baseline before the operation and 1 hour after the skin incision beat per minute,systolic blood pressure baseline before operation and 1 hour after the skin incision mmHg,diastolic blood pressure baseline before operation and 1 hour after the skin incision mmHg,blood suger baseline before operation and at post anesthetic care unit mg per dL

Countries

Thailand

Contacts

Public ContactThanyarat Prommahachai

Udon Thani hospital

pthanya17@gmail.com0812663420

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026