CIN2+ lesion in woman positive with positive high-risk HPV infection with normal cervical cytologic result Cervical cancer screening, Cytology, HPV testing, Dual staining
Conditions
Interventions
Woman with positive high-risk HPV with normal cervical cytology (NILM)
Diagnostic
Woman with positive high-risk HPV with normal cytology
Sponsors
Faculty of Medicine, Srinakharinwirot University
Eligibility
Sex/Gender
Female
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Women aged 25-65 years who receive examination at the Gynecology Outpatient Department, Princess Maha Chakri Sirindhorn Medical Center, Faculty of Medicine, Srinakharinwirot University. 2) Detected of high-risk HPV strains with normal cytology results (NILM). 3) Have no history of CIN 2+ lesions or previous treatment. 4) Consent to participate in the research and have received informed consent.
Exclusion criteria
Exclusion criteria: 1) Pregnancy 2) Repeat cytology test results are abnormal 3) History of CIN 2+ lesions detected or treated 4) Refusal to undergo a cervical dilation or unable to attend a follow-up examination
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection rate for CIN2+ lesion at point when Dual staining was done Dual staining(p16/Ki-67) of cervical liquid-base cytology compared to pathologic result from colposcopic biopsy | — |
Secondary
| Measure | Time frame |
|---|---|
| HPV type related to positive result of dual staining test at point when Dual staining was done Data from Paticipant's specimen | — |
Countries
Thailand
Contacts
Public ContactWarat Duangpirom
Faculty of Medicine, Srinakharinwirot University
Outcome results
None listed