Healthy volunteers bone, probiotic, osteoporosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Thai females aged 20 to 40 years who are legally adult 2. with the ability to read and write in Thai 3. selected to minimize hormonal variability and ensure similar calcium requirements.
Exclusion criteria
Exclusion criteria: 1. Have any chronic diseases, including liver-related conditions. 2. Have gastrointestinal disorders. 3. Have a history of cow milk protein allergy or lactose intolerance. 4. Are currently taking herbal products or dietary supplements of any kind. 5. Are pregnant or breastfeeding. 6. Have a history of bone fractures caused by any accidents. 7. Are taking medications that affect bone mineral density (e.g. bisphosphonates, vitamin D).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bone mineral density 12 weeks after intervention Dual-Energy X-ray Absorptiometry,biochemical markers 12 weeks after intervention Enzyme-Linked Immunosorbent Assay | — |
Secondary
| Measure | Time frame |
|---|---|
| Nutrients intake 12 weeks after intervention questionnaire | — |
Countries
Thailand
Contacts
Faculty of Allied Health Sciences, Burapha University