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Comparison of Fluoride Releasing Versus Conventional Bonds in Development of White Spot Lesion in Orthodontic Patient

Comparison of Fluoride Releasing Versus Conventional Bonds in Development of White Spot Lesion in Orthodontic Patient: A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250731014
Enrollment
48
Registered
2025-07-31
Start date
2024-12-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

White spot lesion associated with fixed orthodontic treatment WSL , Bonding agent, fluoride release

Interventions

Clinical examination was performed on the participating patients and the type of malocclusion they had was determined. Clinical records were taken in the form of: Intra-Oral Photographs (Frontal, Rig
Experimental Other,Active Comparator Other
Fluoride release bond,Conventional bond

Sponsors

Faculty of Dentistry, Sanaa University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1.Requiring full fixed orthodontic appliance treatment. 2. Adult patients aged 16 _30 years old. 3. patient with mild to moderate crowding. 4. optimum oral hygiene. 5. Defect enamel formation is absent in hypocalcification or hypoplasia. 6. Patient with no more than three restored teeth. 7. Orthodontic treatment without extraction during 4 months.

Exclusion criteria

Exclusion criteria: 1.History of fluorosis or other enamel defects. 2. Long-term medication intake due to chronic conditions. 3. The dental baseline visual will be assessed to rule out patients with white spot lesions (WSLs), cavities, or restorations on the buccal surface of upper and lower teeth. 4.Patient took antibiotics during the first four weeks of treatment. 5.Uncooperative patients.

Design outcomes

Primary

MeasureTime frame
development of white spot lesion during orthodontic treatment T0 Pretreatment .T1 after 2 month from treatment .T2 after 4 MONTH FROM TREATMENT Diagnodent pen 2190device

Secondary

MeasureTime frame
Plaque index during orthodontic treatment. Gingival index . bracet failure rate . GI T0 _T1_T2 Silness and loe plaque and gingival index

Countries

Yemen

Contacts

Public ContactSamia Dammaj

Faculty of Dentistry ,Sanaa University

dr.samiadammaj@gmail.com0771706909

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026