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Evaluation of Medical Treatment Outcomes and Development of a Clinical Risk Score for Predicting Clinical Failure in Pediatric Habitual Snoring due to Adenotonsillar Hypertrophy

Evaluation of Medical Treatment Outcomes and Development of a Clinical Risk Score for Predicting Clinical Failure in Pediatric Habitual Snoring due to Adenotonsillar Hypertrophy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20250724004
Enrollment
349
Registered
2025-07-24
Start date
2024-10-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Habitual snoring due to adenotonsillar hypertrophy in children who receive medical treatment habitual snoring, adenotonsillar hypertrophy, obstructive sleep apnea, treatment failure

Interventions

children who had a snoring of less than 3 days/week after medical treatment.,children who had a snoring equal or greater than 3 days/week and/or persistent OSA-related symptoms (gasping, daytime sleep
Treatment,Treatment
Clinical success,Clinical failure

Sponsors

Chulalongkorn University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 15 Years

Inclusion criteria

Inclusion criteria: 1. Children aged 1-15 years who had habitual snoring (equal or more than 3 days per week) due to ATH 2. initially received medical treatment, which was intranasal corticosteroids and/or montelukast.

Exclusion criteria

Exclusion criteria: 1. craniofacial anomalies (e.g., Pierre-Robin sequence, syndromic craniosynostoses, and Treacher Collins syndrome) 2. Down syndrome 3. Prader-Willi syndrome, and 4. Neuromuscular conditions. 5. Children who were treated with other modalities, including adenotonsillectomy and non-invasive positive pressure ventilation (continuous positive airway pressure or bilevel-positive airway pressure) during the medical treatment 6. Children who were lost to follow-up

Design outcomes

Primary

MeasureTime frame
Clinical failure 6 weeks Symptoms (gasping, daytime sleepiness, hyperactivity, apnea, nocturnal enuresis, cyanosis, or fatigue)

Secondary

MeasureTime frame
Factors associated with clinical failure 6 weeks Symptoms (gasping, daytime sleepiness, hyperactivity, apnea, nocturnal enuresis, cyanosis, or fatigue)

Countries

Thailand

Contacts

Public ContactWatit Niyomkarn

Chulalongkorn University

watit.n@chula.ac.th0863678974

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026