Genito-urinary symptom in menopause by pelvic examination, VMI and microbiome Menopause, probiotic, Genitourinary symptom in menopause, VMI, microbiome
Conditions
Interventions
participants take probiotic 1 tab before morning, evening for 30 days, and take pervaginal examination to test Vaginal health index, vaginal maturation index and vaginal microbiome before and after ta
Experimental Dietary Supplement,Placebo Comparator No treatment
Sponsors
Faculty of Medicine Research Grant
Eligibility
Sex/Gender
Female
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Menopause, age > 40 year include : surgical menopause, early menopause 2. amenorrhea > 12 months after Last menopause period 3. Genito-urinary symtpom occur at least 1 times in 1 month, 4. determine to use probiotic
Exclusion criteria
Exclusion criteria: 1. History of taking hormone or lubricant for improve symptom of menopause in last 6 months, 2. History of allergy of probiotic, 3. History to use about product of probiotic : yoghurt, probiotic within 2 weeks, 4. History of pelvic infection within 4 weeks, 5. Severe genitourinary symptoms by pelvic examination, test pH
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vaginal maturation index before and after take probiotic/placebo Cytology of vaginal epithelium | — |
Secondary
| Measure | Time frame |
|---|---|
| microbiome before and after take probiotic vaginal microbiome | — |
Countries
Thailand
Contacts
Public ContactSappawit Lertlerphant
Chiangmai university
Outcome results
None listed