Head and Neck cancer patients Enteral nutrition, head and neck cancer, nutritional support, nutritional status, randomized con-trolled trial, tube feeding
Conditions
Interventions
Sponsors
Prince of Songkla University
Faculty of Medicine, Prince of Songkla University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age 18 years or older 2. Willing to cooperate with treatment and able to provide reliable information 3. Diagnosed with head and neck cancer, completed standard treatment, and currently receiving enteral nutrition via NG feeding or PEG 4. Not currently participating in any other medical nutrition research studies 5. Glomerular filtration rate greater than 30 6. Not classified as significant risk for refeeding syndrome according to NICE guideline, defined as follows 6.1 Body mass index less than 16 kilograms per square meter 6.2 Unintentional weight loss greater than 7 point 5 percent in 3 months or greater than 10 percent in 6 months 6.3 No food intake for 7 days or intake less than 50 percent of requirement for 5 days during acute illness or less than 50 percent for 1 month without illness 6.4 Evident loss of subcutaneous fat or muscle mass 6.5 High risk due to existing comorbidities 7. Laboratory results for refeeding syndrome monitoring are within normal limits 8. No history of neuropathy or stroke and able to perform hand grip strength test
Exclusion criteria
Exclusion criteria: 1. Volunteers with allergies to any ingredients in the study products 1.1 PSU Blen: chicken, mung beans, rice bran oil, soybeans, maltodextrin 1.2 Blendera: sugar, MCT oil, rice bran oil, soybeans, maltodextrin 2. Patients with diabetes due to the presence of sugar in Blendera 3. Patients diagnosed with gastrointestinal obstruction, gastrointestinal dysmotility, or diarrhea more than 3 times per day 4. Patients with liver disease classified as Class C by Child Pugh Classification 5. Patients with impaired kidney function (serum creatinine greater than 2 mg per dL) 6. Pregnant or breastfeeding patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SGA 1 month PG-SGA | — |
Secondary
| Measure | Time frame |
|---|---|
| hand grip strength 1 month hand grip strength,Body weight 1 month Body weight,BMI 1 month BMI,Serum albumin 1 month Serum albumin,Hemoglobin level 1 month Hemoglobin level,Platelet count 1 month Platelet count | — |
Countries
Thailand
Contacts
Public ContactManupol Tangthongkum
Faculty of Medicine, Prince of Songkla University
Outcome results
None listed