Full-Endoscopic Interlaminar Lumbar Discectomy Versus Unilateral Biportal Interlaminar Lumbar Discectomy for a single level lumbar disc herniation: A randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250718001

Enrollment

Registered

2025-07-18

Start date

2024-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar disc herniation causing nerve root compression, resulting in radicular pain or neurological symptoms that require surgical intervention. Lumbar Disc Herniation Intervertebral Disc Displacement Endoscopic Spine Surgery Biportal Endoscopic Surgery Minimally Invasive Surgical Procedures Discectomy Radiculopathy Randomized Controlled Trial Spinal Diseases Surgical Outcomes

Interventions

Patients assigned to the UBE group will undergo discectomy via two small incisions (approximately 1 cm each) on the ipsilateral side of the herniated disc. The procedure is performed under general ane

Experimental Procedure/Surgery,Experimental Procedure/Surgery

Full-Endoscopic Spine Surgery (FESS/PELD),Unilateral Biportal Endoscopic Spine Surgery (UBE)

Eligibility

Sex/Gender

All

Age

15 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Male or female patients aged 15 to 70 years. 2. Diagnosed with lumbar disc herniation presenting with radiating leg pain on one side. 3. MRI-confirmed single-level lumbar disc herniation consistent with the patient's symptoms. 4. Failed conservative treatment within 3 months, with persistent pain or numbness interfering with daily activities and meeting surgical indication. 5. Presence of motor weakness (below grade 4) in toes or foot on one side at initial assessment. 6. Able to complete follow-up and clinical outcome evaluation for at least 6 months postoperatively.

Exclusion criteria

Exclusion criteria: 1. Patients who are unable to complete follow-up and outcome assessment within 6 months postoperatively. 2.Patients with a history of prior lumbar discectomy at the same affected level (recurrent lumbar disc herniation). 3. Patients diagnosed with other spinal pathologies such as spondylodiscitis or spinal tumors. 4. Patients with cognitive impairment that prevents them from completing questionnaires.

Design outcomes

Primary

Measure	Time frame
Clinical outcome at post operative 1 month,3 months and 6 months at 6 months after end of the surgery Oswestry Disability Index (ODI) score and Visual analogue score (VAS) score at 1,3,6 months	—

Secondary

Measure	Time frame
Perioperative outcomes admission period Operative time Blood loss Length of hospital stay	—

Countries

Thailand

Contacts

Public ContactWeerasak Sutipornpalangkul

Mahidol university

orthoresearch.si@gmail.com024197968

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026