Patients in Faculty of Dentistry, PSU who undergo bimaxillary orthognathic surgery orthognathic surgery, multimodal analgesia, morphine requirements, VAS score
Conditions
Interventions
Ketorolac (30 mg) 1 ml IM after orthognatic surgery,Normal saline solution 1 ml IM after orthognathic surgery
Experimental Drug,Placebo Comparator Drug
Group A,Group B
Sponsors
Ministry of Higher Education, Science, Research, Research and innovation, Prince of Songkla University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Inform consent to the research 2. ASA classification I, II 3. Patient age between 18-40 4. Patients undergo bimaxillary orthognathic surgery 5. Patients have performance to administer morphine-based intravenous Patient-Controlled Analgesia and have ability to assess postoperative pain score via VAS during the first 24 hours after the surgery.
Exclusion criteria
Exclusion criteria: 1. Patients undergo Subapical Osteotomy technique in maxilla or mandible without combining Lefort I osteotomy, bilateral sagittal split ramus osteotomy or intraoral vertical ramus osteotomy. 2. Patients allergic to ketorolac and morphine. 3. Patients have contraindications to use ketorolac and to take medication that interferes ketorolac.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| morphine consumption 24 hours after the surgery mg | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score 24 hours after the surgery VAS | — |
Countries
Thailand
Contacts
Public ContactSurapong Vongvatcharanon
Prince of Songkla University
Outcome results
None listed