Coronavirus disease 2019 (COVID 19) is an infectious disease of the respiratory system that can cause severe pneumonia and even death. The COVID 19 pandemic has become a serious public health issue. Physiologic changes of respiratory and immunity system increase the risk and severity of infection. Pregnant women particularly those admitted to the intensive care units and those receiving extracorporeal membrane oxygenation are at higher risk of mortality than nonpregnant women. Furthermo
Conditions
Interventions
pregnant women who were vaccinated against
COVID-19 during pregnancy at antenatal care clinic
and delivered at Venerable Thawisak Jutindharo
Hospital between May 2022 and October 2022
Other
pregnancy with COVID 19
Sponsors
None listed
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: pregnant women who were vaccinated against COVID-19 during pregnancy and who received antenatal care clinic and delivered their babies at Venerable Thawisak Jutindharo Hospital between May 2022 and October 2022 inclusion criteria 1) women with single pregnancy, 2) those aged over 18 years, 3) those who have been vaccinated against COVID-19, 4) those who can speak and communicate in Thai, and 5) those who do not have a family history of COVID-19 or close contact with people with the condition. In particular, the participants should have received at least two vaccine doses, a proof of vaccination, or a history of vaccination in the Ministry of Public Health application (without the need for further vaccination according to the normal formula or period)
Exclusion criteria
Exclusion criteria: The exclusion criteria were as follows: 1) pregnant women with COVID-19 or those with a history of the infection before pregnancy, 2) those with a history of close contact with a person infected with COVID-19, 3) those with immunodeficiency diseases such as congenital immunodeficiency, 4) those with HIV who are receiving immunosuppressive drugs, and 5) those with maternal or fetal crisis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the level of immunity against SARS-CoV-2 in the neonatal umbilical cord at delivery level of immunity against SARS-CoV-2 was presented as units per milliliter | — |
Secondary
| Measure | Time frame |
|---|---|
| the association between the duration from the last vaccine dose to delivery and the level of immunity against the SARS-CoV-2 in the neonatal umbilical cord significant P less than0.05 association,the level of immunity against SARS-CoV-2 in maternal blood at delivery level of immunity against SARS-CoV-2 was presented as units per milliliter | — |
Countries
Thailand
Contacts
Public ContactLadakan Lertvanavit
Venerable Thawisak Jutindharo Hospital
Outcome results
None listed