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Evaluation of Microneedling Technique with and without Using Ascrobic Acid in Gingival Depigementation : A Split-Mouth Randomized Clinical Trial

Evaluation of Microneedling Technique with and without Using Ascrobic Acid in Gingival Depigementation : A Split-Mouth Randomized Clinical Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250714002
Enrollment
20
Registered
2025-07-14
Start date
2025-07-13
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Physiologic gingival pigmentation microneedling - pigmentation - vitamin C

Interventions

Dermapen will laid perpendicular to the gingival surface and the MN will carried out in horizontal, vertical, and diagonal directions for four to five times for the whole hyperpigmented gingival surfa
Microneedling without vitamin C,Microneedling with vitamin C

Sponsors

Self - funded
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Patients with age ranges from 18 to 45 years . 2. Phsiological melanin-related gingival hyperpigmentation. 3. Periodontal health . 4. Patients free of systemic diseases.

Exclusion criteria

Exclusion criteria: 1. Previous treatment for gingival pigmentation during the last 6 month. 2. Pregnant or breastfeeding women. 3. Smoking patient. 4. Patients who are taking medication known to affect gingival colour. 5. Qat chewers 6. Patients have history with vitamine C sensitivity. 7. Patients with anterior prostheses appliance and active caries.

Design outcomes

Primary

MeasureTime frame
Gingival depigmentation score 3months Dummett oral pigmentation index (DOPI)

Secondary

MeasureTime frame
Patient satisfaction 3 months Visual Analogue Scale (VAS)

Countries

Yemen

Contacts

Public ContactSamar Alshamery

Sana'a University

SamarAlshamery123@gmail.com771213253

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026