Cardiorenal syndrome Heart failure Acute kidney injury Acute kidney injury, Acute heart failure, Cardiorenal syndrome, Biomarkers
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age more than 18 years with hospitalized with a physician confirmed diagnosis of AHF and an NT-proBNP level more than 300 pg/mL
Exclusion criteria
Exclusion criteria: 1.pregnancy 2. CKD stage 5, current kidney replacement therapy or post-kidney transplantation 3. AKI stage 3 at presentation or need for acute dialysis 4. Suspected urinary tract infection or urine white blood cell count > 5 cells/high-power field, urine red blood cell count > 5 cells/high-power field, baseline UPCR > 3 g/g Cr, suspected hematologic malignancy or multiple myeloma, rhabdomyolysis, intravascular hemolytic anemia, or refusal to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AKI on day 7 day 7 after admission Serum creatinine | — |
Secondary
| Measure | Time frame |
|---|---|
| AKI on Day 2 AKI within 48 hours after admisison Serum creatinine,AKD on day 28 28 days after admission Serum creatinine | — |
Countries
Thailand
Contacts
Navamindradhiraj University