postoperative pain in total knee arthroplasty genicular nerve block postoperative pain management in total knee arthroplasty
Conditions
Interventions
In the cGNI group, 6 ml of 20 ml of 0.5% bupivacaine (ASPENTM) undiluted will be administered at each site including
superior lateral genicular nerve area, superior medial genicular nerve area, and in
Experimental Drug,Active Comparator Drug
high-concentrated intraoperative genicular nerve infiltration (cGNI),periarticular infiltration (PAI)
Sponsors
Nakornping Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing unilateral or bilateral total knee arthroplasty (TKA) from July 2024 to April 2026 2. Age 40-80 years old 3. Diagnosed with knee osteoarthritis 4. Chronic knee pain for at least 6 months
Exclusion criteria
Exclusion criteria: 1. Allergic to any of the study drugs 2. Regular opioid use 3. Renal insufficiency 4. Cardiac disease 5. Deep vein thrombosis 6. History of steroid or immunosuppressive drug used within 6 months 7. Diabetes mellitus (HbA1C >7.5 on preadmission testing) 8. Hypercoagulable disorder 9. Previous ipsilateral knee surgery 10. Inability to communicate pain score 11. Declined to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score at rest 4 hr, 24 hr, 48 hr postoperatively Visual analog scale (VAS) pain score (0-10),Pain score on motion 24 hr, 48 hr postoperatively Visual analog scale (VAS) pain score (0-10) | — |
Secondary
| Measure | Time frame |
|---|---|
| Amount of opioid consumption at 24 hr, 48 hr postoperatively milligram,Time to first rescue opioid request of first rescue opioid hour,Knee range of motion 24 hr, 48 hr postoperatively degree, An average of 3 measurements using goniometer,Length of stay admission days after surgery days,Satisfaction discharge date points 0-10 | — |
Countries
Thailand
Contacts
Public ContactPatcha Promlikhitkul
Nakornping Hospital
Outcome results
None listed