The effectiveness of cryotherapy in alleviating pain after single visit root canal treatment in single rooted teeth.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250628001

Enrollment

Registered

2025-06-28

Start date

2023-01-16

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain measurement cryotherapy, root canal treatment ,post operative pain.

Interventions

After root canal treatment, the tooth is irrigated with cold saline.,After root canal treatment, the tooth is irrigated with room temperature saline.

Experimental Drug,No Intervention Drug

cold saline,room temperature saline

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1 Adult patients age range between 18 to 60 years. 2 Irreversible pulpitis with normal apical tissue. 3 Irreversible pulpitis with symptomatic apical periodontitis .

Exclusion criteria

Exclusion criteria: 1.retreatment cases 2. pulpal necrosis 3, abscess, 4 severe periodontal disease, 5 immature apex, 6. resorption, 7. systemic compromise, 8 pregnancy, 9mental disability 10.allergy to local anesthesia

Design outcomes

Primary

Measure	Time frame
pain 24 hours visual analogue scale	—

Secondary

Measure	Time frame
N/A N/A N/A	—

Countries

Pakistan

Contacts

Public ContactNina Ayaz

fatima jinnah dental college and hospital.

ninaahabib03@gmail.com923340766606

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026