The degree of gingival pigmentation will be evaluated using the Dummett-Gupta Oral Pigmentation Index (DOPI), Hedin melanin index (HMI), - A Visual Analogue Scale (VAS), The level of patient'
Conditions
Interventions
Microneedling will be performed using a Dermapen device, with a solution of ascorbic acid 1,000 mg / mL mixed with saline applied to the gingiva for 10 minutes. The Dermapen will be positioned perpend
Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery
Microneedling with ascorbic acid,Mesotherapy with ascorbic acid
Sponsors
Hospital of Stomatology of Sanaa University
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Male and female, age ranges of 18 to 35 years. 2. Individuals with moderate to severe anterior gingival pigmentation. 3. Good general health without any systemic diseases.
Exclusion criteria
Exclusion criteria: 1. Individuals with periodontal disease and with a thin gingival phenotype. 2. Individuals who smoke or those who have tobacco related habits. 3. Pregnant or lactating women. 4. Non vital anterior teeth, active caries and prosthesis. 5. Hypersensitivity to ascorbic acid. 6. Who had previous depigmentation procedure. 7. Use of medications that promote gingival pigmentation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gingival depigmentation and number of melanocyte per field Baseline, third month, sixth month Measured by (DOPI), (HMI), VAS, Likert and histopathologial examination | — |
Secondary
| Measure | Time frame |
|---|---|
| histopathological examination baseline, sixth month Two tissue samples will be obtained from each patient at baseline and 6 months after treatment by the same operator for histological analysis. | — |
Countries
Yemen
Contacts
Public ContactWardah Al Otab
Stomatology hospital of Sanaa universty
Outcome results
None listed