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Effectiveness of a Low-Carbohydrate Diet on Glycemic Control in Patients with Type 2 Diabetes: A Randomized Controlled Trial

Effectiveness of a Low-Carbohydrate Diet on Glycemic Control in Patients with Type 2 Diabetes: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250627002
Enrollment
112
Registered
2025-06-27
Start date
2024-12-11
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by elevated blood glucose levels due to insulin resistance and/or impaired insulin secretion. Poor glycemic control in patients with T2DM increases the risk of both microvascular and macrovascular complications. In Thailand, T2DM is highly prevalent, especially in aging populations and those with sedentary lifestyles. Despite pharmacologic treatment, a significant proportion of patients remain with uncontrolled blood s

Interventions

Participants in this group received individualized counseling and education focused on a low-carbohydrate diet. The dietary goal was to reduce carbohydrate intake to under 130 grams per day or less th
s diabetes clinic. The education was delivered over 24 weeks through monthly follow-up visits. It included general information on diabetes self-care such as healthy eating, regular physical activity,
Experimental Behavioral,No Intervention Behavioral
Low-Carbohydrate Diet,Standard Diabetes Education

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Adults aged 18 years or older 2.Diagnosed with type 2 diabetes mellitus (T2DM) 3.Stable medication or dietary plan for at least 3 months prior to enrollment 4.Able to attend follow-up appointments and comply with study procedures 5.Able to read, write, or understand Thai 6.Provide written informed consent to participate in the study

Exclusion criteria

Exclusion criteria: 1.Diagnosed with severe chronic kidney disease with eGFR less than 30 mL/min/1.73 m2 2.Diagnosed with chronic liver disease or liver cirrhosis 3.Currently undergoing treatment for cancer 4.Pregnant or breastfeeding 5.Diagnosed with dysphagia or any malabsorption disorder 6.Diagnosed with severe psychiatric disorder that may affect participation 7.Use of medications that significantly affect glucose metabolism

Design outcomes

Primary

MeasureTime frame
Glycated hemoglobin level 24 weeks Milligrams percent

Secondary

MeasureTime frame
Fasting blood glucose level 24 weeks milligrams per deciliter,Triglyceride level 24 weeks milligrams per deciliter

Countries

Thailand

Contacts

Public ContactPanlapar Inlao

Rattanaburi Hospital

Panlapar21856@gmail.com0944787259

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026