the study is conducted in healthy human volunteers who will undergo single one stage implant surgery in the posterior region. Cold plasma, Dental implant, Wound healing, Bacteria load, Bleeding on Probing, Bone resorption
Conditions
Interventions
Cold plasma will be applied directly to the dental implant wound immediately after the implant placement with a medical grade cold plasma device for 15 minutes. ,The participant will receive standard
Experimental Device,No Intervention No treatment
Group A,Group B
Sponsors
Chulalongkorn University
Mirari (Thailand) Ltd.,
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged between 20 and 80 years 2. Both male and female 3. Single stage implant surgery in the posterior region 4. Good systemic health (ASA Class I or II) 5. Both immediate and delayed implant placement 6. Adequate bone density for implant placement 7. Non-smokers or ceased smoking for at least 6 months before surgery 8. No history of periodontal diseases or in maintenance phase 9. Willing and able to attend all follow-up appointments
Exclusion criteria
Exclusion criteria: 1. Chronic use of corticosteroids or anti-inflammatory drugs 2. Use of medications affecting bone metabolism (e.g. bisphosphonates, etc.) 3. History of radiation therapy in the head and neck region 4. Patients who require or have recently undergone bone grafting before implant placement 5. Active infections or periodontal diseases in the surgical area 6. Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Outcomes at Immediate, 3rd and 6th months and 1 year after implant placement Marginal Bone Loss (MBL),Implant Stability Quotient (ISQ) at immediate and 3rd month after implant placement Resonance Frequency Analysis (RFA) | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound Healing Outcomes at 2nd and 4th weeks after implant placement Wound Characteristics,Wound Healing Characteristics at 2nd and 4th weeks after implant placement Bleeding on Probing (BOP),Bacterial Count Reduction at 2nd and 4th weeks after implant placement Reduction Bacteria Count (Aerobic & Anaerobic) | — |
Countries
Thailand
Contacts
Public ContactMyo Thiri Win
Faculty of Dentistry, Chulalongkorn University
Outcome results
None listed