osteoporosis, sarcopenia, and hypovitaminosis D in patients with end stage knee osteoarthritis undergoing knee arthroplasty Total knee arthroplasty Osteoporosis Sarcopenia Osteosarcopenia Prevalence Treatment
Conditions
Interventions
Postmenopausal women and men aged 50 years or older with advanced-stage knee osteoarthritis who were scheduled for elective TKA or unicompartmental knee arthroplasty (UKA).
Other
Elective knee arthroplasty patients
Sponsors
Faculty of Medicine Siriraj Hospital, Mahidol university, Thailand
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Postmenopausal women and men aged 50 years or older 2. Advanced-stage knee osteoarthritis 3. Scheduled for elective TKA or unicompartmental knee arthroplasty (UKA).
Exclusion criteria
Exclusion criteria: 1. Revision knee arthroplasty, 2. Patients who were unable to comprehend or respond to questionnaires 3. Patients who can't perform or can not understand physical performance assessments using five time chair stand test 4. patients who were unwilling to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of osteoporosis within 3 months of surgery BMD within 3 months post-surgical treatment via a dual-energy X-ray absorptiometry scanner,Prevalence of sarcopenia one day prior to elective knee arthroplasty appendicular skeletal muscle mass (ASM) using bioelectrical impedance analysis (BIA), handgrip strength assessment, and physical performance tests using five time chair stand test | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary osteoporosis and hypovitaminosis D one day prior to elective knee arthroplasty fasting blood sample of Ca, PO4, Alb, PTH, BUn Cr, Vitamin D | — |
Countries
Thailand
Contacts
Public Contactkorawish mekariya
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed