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Prevalence of Macrolide-Resistant Mycoplasma pneumoniae in Children and Adolescents with Community-Acquired Pneumonia: A Prospective Study in Thailand

Macrolide-Resistant Mycoplasma pneumoniae among patients with community-acquired pneumonia in Siriraj Hospital

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20250618004
Enrollment
224
Registered
2025-06-18
Start date
2014-01-16
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

community-acquired pneumonia (CAP) Macrolide-resistant Mycoplasma pneumoniae, Community-acquired pneumonia, Mycoplasma

Interventions

Children and adolescents aged 1 month to 18 years who were diagnosed with CAP and received care at Siriraj Hospital.
Diagnostic
Pediatric CAP patients

Sponsors

Siriraj Research and Development Fund
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Months to 18 Years

Inclusion criteria

Inclusion criteria: 1. children and adolescents, 2. diagnosed with CAP , 3. receiving care at Siriraj Hospital, including both outpatients and inpatients, 4. Patients or their legal guardians voluntarily agree to participate in the study by signing the informed consent form

Exclusion criteria

Exclusion criteria: 1. identification of respiratory pathogens other than M. pneumoniae in nasopharyngeal samples, 2. onset of respiratory symptoms more than 72 hours after hospital admission.

Design outcomes

Primary

MeasureTime frame
MRMP infection status At diagnosis Real-time Polymerase Chain Reaction and macrolide resistance gene sequencing

Secondary

MeasureTime frame
Treatment responses 72 hours after treatment, Time to defervescence, End of treatment Clinical symptom resolution,Factors associated with MRMP infection At the beginning of study History of Macrolide and antibiotic use within 3 months, Hospitalization in the past 3 months, Demographic data (age, sex, underlying condition, no. of household members), daycare attendance

Countries

Thailand

Contacts

Public ContactWanatpreeya Phongsamart

Siriraj Hospital Mahidol University

wanatpreeya@gmail.com6624195671

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026