Malnutrition-Inflammation, Sarcopenia, and Vascular Calcification in Maintenance Hemodialysis Patients at Siriraj Hospital

The relationship between malnutrition-inflammation, sarcopenia and the progression of abdominal aortic calcification in maintenance hemodialysis patients , and their association with short-term and long-term mortality rates

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20250617005

Enrollment

350

Registered

2025-06-17

Start date

2024-11-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ESRD on chronic HD Malnutrition-inflammation Sarcopenia Vascular calcification ESRD chronic HD Malnutrition-inflammation Sarcopenia Vascular calcification

Interventions

ESRD patients currently on chronic hemodialysis treatment

Diagnostic

ESRD on chronic HD

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnosis of ESRD currently on chronic HD

Exclusion criteria

Exclusion criteria: 1. Severe mobility problem ex. weakness, history of amputation, disease effecting mobility 2. Can't follow to commands 3. History of hospitalization within 1 month before enrollment 4. Contraindication to the use of bioimpedance study ex. metals, pacemakers 5. Can't perform handgrip strength test ex. amputaiont, stroke, severe arthritis 6. End-stage cancer 7. Severe systemic infection

Design outcomes

Primary

Measure	Time frame
5-year Mortality 5 year from enrollment Survival analysis and it's association with malnutrition-inflammation status, sarcopenia and vascular calcification,1-year Mortality 1 year from enrollment Survival analysis and it's association with malnutrition-inflammation status, sarcopenia and vascular calcification,Accuracy of SARC-F in screening sarcopenia at enrollment sensitivity and specificity assessment	—

Measure

Time frame

5-year Mortality 5 year from enrollment Survival analysis and it's association with malnutrition-inflammation status, sarcopenia and vascular calcification,1-year Mortality 1 year from enrollment Survival analysis and it's association with malnutrition-inflammation status, sarcopenia and vascular calcification,Accuracy of SARC-F in screening sarcopenia at enrollment sensitivity and specificity assessment

—

Secondary

Measure	Time frame
Accuracy of SGA, MIS, SARC-Calf in screening sarcopenia at enrollment sensitivity and specificity assessment,Prevalence of sarcopenia in ESRD patients on chronic HD at enrollment Prevalence,Prevalence of cachexia in ESRD patients on chronic HD at enrollment Prevalence,Association of sarcopenia and cachexia and patient's outcomes (hospitalization and mortality) 1 year and 5 year Survival analysis and multivariate analysis,Association of vascular calcification and patient's outcomes (hospitalization and mortality) 1 year and 5 year Survival analysis and multivariate analysis, assess vascular calcification by plain film and PWVI/CAVI,Association of abdominal aorta calcification score and PWVI/CAVI in ESRD patients on chronic HD at enrollment association analysis	—

Measure

Time frame

Accuracy of SGA, MIS, SARC-Calf in screening sarcopenia at enrollment sensitivity and specificity assessment,Prevalence of sarcopenia in ESRD patients on chronic HD at enrollment Prevalence,Prevalence of cachexia in ESRD patients on chronic HD at enrollment Prevalence,Association of sarcopenia and cachexia and patient's outcomes (hospitalization and mortality) 1 year and 5 year Survival analysis and multivariate analysis,Association of vascular calcification and patient's outcomes (hospitalization and mortality) 1 year and 5 year Survival analysis and multivariate analysis, assess vascular calcification by plain film and PWVI/CAVI,Association of abdominal aorta calcification score and PWVI/CAVI in ESRD patients on chronic HD at enrollment association analysis

—

Countries

Thailand

Contacts

Public ContactKornchanok Vareesangthip

Siriraj hospital, Mahidol University

kornchanok.var@mahidol.ac.th024198383

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026