Role of antibiotic prophylaxis in cirrhosis Child-Turcotte-Pugh A patients with upper gastrointestinal bleeding Antibiotic prophylaxis Cirrhosis Child-Turcotte-Pugh A Upper gastrointestinal bleeding
Conditions
Interventions
No antibiotic prophylaxis in this group,Patient will receive antibiotic for prophylaxis (standard of care) for at least 3 days to maximum of 5 days
(Ceftriaxone 2 g intravenous every 24 hours or Cipro
No antibiotic prophylaxis,Antibiotic prophylaxis
Sponsors
Phramongkutklao hospital
The Gastroenterological Association of Thailand
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: At least 20 years of age Cirrhosis Child-Turcotte-Pugh A Upper gastrointestinal bleeding
Exclusion criteria
Exclusion criteria: Hepatocellular carcinoma Advanced stage malignancy Septic shock Failure to stop bleeding by endoscopic therapy Diagnosis with infection Deny to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infection rate until 6 weeks after event of bleeding infection event | — |
Secondary
| Measure | Time frame |
|---|---|
| 5-day rebleeding rate 5 days after the first bleeding event rebleeding event,6-week rebleeding rate 6 weeks after the first bleeding event rebleeding event,6-week mortality rate until 6 weeks after event of bleeding number of death | — |
Countries
Thailand
Contacts
Public ContactPavitra Charoensrisakkul
Phramongkutklao hospital
Outcome results
None listed