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Efficacy of Er-YAG laser for decontamination of dental implant surfaces: an in vitro study

Efficacy of Er-YAG laser for decontamination of dental implant surfaces: an in vitro study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250603004
Enrollment
12
Registered
2025-06-03
Start date
2025-08-20
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Contaminated implant surface Er: YAG laser Erbium-YAG laser Biofilm Decontamination Implant surface

Interventions

Acrylic appliance for collecting oral biofilm from participants
Experimental No treatment
Collecting biofilm

Sponsors

Faculty of dentistry, Prince of Songkla University
Lead Sponsor
Faculty of Dentistry&#039
Collaborator
s Research Fund and the Graduate Study Support Fund of the Department of Surgery, Faculty of Dentistry
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Healthy adults (Age >18) (no history of systemic diseases or infectious diseases) 2.Presence of enough teeth to support the acrylic appliance 3.No history of radiotherapy and chemotherapy 4.No use of antibiotics during the last three months 5.Non-smokers

Exclusion criteria

Exclusion criteria: 1.Patient who wearing removable denture to prevent fungal contamination 2.Lost multiple teeth that prevent the installment of a stable occlusal appliance 3.Inability to wear the acrylic appliance because of severe pharyngeal reflex 4.Subjects with contraindications to wearing an intraoral appliance, such as chronic obstructive pulmonary disease or severe sleep apnea. 5.Subjects with known allergies to acrylic, titanium, denture adhesive.

Design outcomes

Primary

MeasureTime frame
Numbers of bacteria on the implant surfaces At the time of specimen collection Colony forming unit,Percentage of bacterial reduction on the implant surface At the time of specimen collection Live/dead cell assay

Secondary

MeasureTime frame
Surface morphology At the time of specimen collection Scanning electron microscope ,Surface roughness At the time of specimen collection Average roughness(Ra),Surface wettability At the time of specimen collection Contact angle,Surface temperature change At the time of specimen collection Temperature after intervention by Er: YAG laser,Osteoblastic cell Attachment and proliferation At the time of specimen collection Scanning electron microscope

Countries

Thailand

Contacts

Public ContactNattawut Thuaksubun

Faculty of Dentistry, Prince of Songkla University

nuttawut.t@psu.ac.th0954592492

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026