Hepatocellular Carcinoma fecal bile acids, hepatocellular carcinoma
Conditions
Interventions
Advanced stage hepatocellular carcinoma (BCLC-C) patients
Screening
HCC group
Sponsors
Faculty of Medicine, Khon Kaen university
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Disease group (HCC) use data from research HE661280 Inclusion 1. Advanced stage hepatocellular carcinoma (BCLC-C) patients with age greater than 18 2. Never diagnosed other malignancy or complete treatment and complete remission of other malignancy more than 5 years 3. Place of birth at north eastern of Thailand
Exclusion criteria
Exclusion criteria: Disease group (HCC) use data from research HE661280 Exclusion 1. The diagnosis is hepatocellular-cholangiocarcinoma 2. current use of drugs or products that effect gut microbe e.g. antibiotics, proton pump inhibitors 3. Taking products that compose of probiotics, ursodeoxycholic acid within 14 days 4. The behavior of eating specific foods, such as eating vegetarian, vegan, or fasting during certain periods. 5. Unable to collect stool samples or only able to collect an insufficient amount for testing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fecal bile acid level at time of study enrollment 1H NMR spectroscopy | — |
Secondary
| Measure | Time frame |
|---|---|
| Association of fecal bile acid level and prognostic factors for HCC at the time of enrollment review laboratory and patient data in hospital database | — |
Countries
Thailand
Contacts
Public ContactNititorn Watthanakul
Faculty of Medicine, Khon kaen university
Outcome results
None listed