Lichen planopilaris, frontal fibrosing alopecia Lichen planopilaris, frontal fibrosing alopecia
Conditions
Interventions
PRP was prepared using a double spin technique. First, 12 mL of whole blood was collected in two 6 mL ethylenediaminetetraacetic acid tubes. The tubes were centrifuged at 2000 RPM for 10 minutes in a
Experimental Biological/Vaccine,Placebo Comparator Other
Platelet rich plasma (PRP) injection,NSS (placebo)
Sponsors
Faculty of Medicine Siriraj Hospital, Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged equal or more than 18 years were eligible if they had confirmed LPP or FFA (based on clinical and/or histopathological findings at the hair clinic, Siriraj Hospital) 2. All participants also had no disease progression for at least 6 months, with or without receiving standard treatments. 3. All participants exhibited lesions of comparable severity on both sides of the scalp.
Exclusion criteria
Exclusion criteria: 1. Co-existing with other hair loss-causing conditions (eg, anemia, diabetes, thyroid disorders, autoimmune diseases, telogen effluvium) 2. Use of medications known to induce hair loss (eg, oral retinoids, antidepressants, warfarin); active scalp infections 3. Contraindications to PRP (eg, clotting disorders, HIV, hepatitis B, hepatitis C) 4. Pregnancy and breastfeeding 5. Having a history of allergy to local anesthetics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dermatologist evaluation week 20 7 point scale,Patient satisfaction week 20 7 point scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects Week 0, 4, 8 Example: pain, erythema, swelling, pruritus | — |
Countries
Thailand
Contacts
Public ContactKanchalit Thanomkitti
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed