The post-acne erythema and hyperpigmentation who have even on both side of the face. Post-acne erythema, Post inflammatory hyperpigmentation, picosecond laser, lasers
Conditions
Interventions
One side of the face will be treated with picosecond 1,064 nm laser in fractional mode utilized micro-lens array handpiece with low fluent for 3 times in every 2 weeks.,One side of the face will be tr
Active Comparator Procedure/Surgery,Experimental Procedure/Surgery
Fractional picosecond 1,064 nm laser,Toning picosecond 1,064 nm laser
Sponsors
Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Participants must be older than 18 years old 2. Participants must have even post-acne erythema and hyperpigmentation even on both sides of the face 3. Participants may have active acne, but less than 10 lesions per sides and the size must less than 10 mm in diameter. And both side have the count acne lesions in the same amount within 3 lesions.
Exclusion criteria
Exclusion criteria: 1. Applying retinol within 7 days 2. Using isotretinoin within 30 days 3. Applying azelaic acid within 7 days 4. Using benzoyl peroxide within 7 days 5. Having severe acne, overall count more than 20 lesions or having more than 10 lesions on one side of the face or having one lesion in 10 or more mm size 6. having active skin diseases including skin infection, psoriasis, vitiligo on the face. 7. Having botulinum toxin treatment on the face within 6 past months 8. Having cosmetic treatments, lasers, peelings, microneedle radiofrequency, monopolar radiofrequency within 3 past months. 9. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinician erythema assessment scale 0, 2, 4, 8, 12, and 16 weeks One blinded dermatologist will receive the photographs of the patient and instruct to use the clinician erythema assessment scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| General aesthetic improvement scale 0, 2, 4, 8, 12, and 16 One blinded dermatologist will receive the photographs of the patient and instruct to use the General aesthetic improvement scale .,mean redness score 8, 12, and 16 weeks The mean redness score was calculated from forehead, cheek, and lower cheek assessed by utilizing Antera3D imaging system.,Mean pigment score 8, 12, and 16 weeks The mean pigment score was calculated from forehead, cheek, and lower cheek assessed by utilizing Antera3D imaging system.,mean texture score 8, 12, and 16 weeks The mean texture score was calculated from forehead, cheek, and lower cheek assessed by utilizing Antera3D imaging system.,Pore 8, 12, and 16 weeks The pore will evaluated in average pore size, total pore counts by utilizing Antera3D imaging system,Pain score 0, 2, and 4 weeks The patient will receive the evaluation form in visual analog scale immediate after the laser treatment.,Patient satisfaction score at 8, 12, and 16 weeks The patient satisfaction score will be evaluated by using visual analog scale by comparing the before and after photographs. | — |
Countries
Thailand
Contacts
Public ContactVasanop Vachiramon
Faculty of Medicine Ramathibodi hospital, Mahidol university
Outcome results
None listed