Clinical Impact of Transcranial Focused Ultrasound Stimulation on Human Visual Cortex

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250515007

Enrollment

Registered

2025-05-15

Start date

2022-03-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adults patients with visual acuity worse than 20/70, who also had lesions in the anterior visual pathway but intact visual cortexes. Transcranial focused ultrasound, visual cortex stimulation, blindness, ultrasound stimulation

Interventions

Transcranial-focused ultrasound is a low-intensity ultrasound technique used for brain stimulation, referred to as NeuroFUS (Brainbox Ltd., The Creative Quarter, 8a Morgan Arcade, Cardiff CF10 1AF, UK

Experimental Device

transcranial focused ultrasound stimulation

Eligibility

Sex/Gender

All

Age

30 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1 adult patients 2 visual acuity worse than 20/70, requiring either unilateral or bilateral eye involvement 3 exhibiting lesions in the anterior visual pathway, including any pathology within the orbit, retina, optic nerve, and optic chiasm.

Exclusion criteria

Exclusion criteria: 1 epilepsy 2 congenital blindness 3 unable to communicate

Design outcomes

Primary

Measure	Time frame
visual acuity 30 minutes logmar	—

Secondary

Measure	Time frame
visual perception during stimulation 30 minutes descriptive	—

Countries

Thailand

Contacts

Public ContactPanitha Jindahra

Faculty of Medicine Ramathibodi Hospital

panitha.jin@mahidol.ac.th022011386

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026