Cardiac arrest Cardiac arrest, sustained ROSC, PEEP
Conditions
Interventions
5 PEEP group (comparator group): use PEEP 5 cmH2O in ventilator setting,Zero PEEP group (control group): use PEEP 0 cmH2O in ventilator setting
Experimental Procedure/Surgery,No Intervention No treatment
Five PEEP group,Zero PEEP group
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients aged 18 years and older who present with cardiac arrest at the ED or out-of-hospital cardiac arrest
Exclusion criteria
Exclusion criteria: 1. Do Not Resuscitate (DNR) order 2. Traumatic cardiac arrest 3. Pregnancy 4. Termination of resuscitation before 30 minutes 5. Sign of irreversible death 6. Suspected pneumothorax 7. Achieved return of spontaneous circulation before being randomized
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sustained return of spontaneous circulation 20 minutes after return of spontaneous circulation persistence of signs of circulation for at least 20 minutes after return of spontaneous circulation | — |
Secondary
| Measure | Time frame |
|---|---|
| partial pressure of oxygen in arterial blood and partial pressure of carbon dioxide in arterial blood change 10-20 minute after first Arterial blood gas Arterial blood gas measurement at pre- and post- apply ventilation,Neurological outcome 3-month Cerebral performance category (CPC) score,Survival outcome 1-month and 3-month Follow up survival | — |
Countries
Thailand
Contacts
Public ContactKarn Suttapanit
Emergency department, Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed