Hypotension during induction of anesthesia and supraglottic airway (LMA) insertion
Conditions
Interventions
Participants receive fentanyl 1 mcg/kg IV two minutes before propofol 2 mg/kg IV. Additional propofol 0.5 mg/kg boluses are given if needed for optimal insertion conditions.,Participants receive an eq
Active Comparator Drug,Placebo Comparator Drug
Fentanyl preinduction,Saline preinduction
Sponsors
Department of Anesthesiology, Faculty of medicine, Chiang Mai University
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged between 20 and 65 years 2. Patients who undergoing elective surgery requiring LMA insertion 3. American Society of Anesthesia (ASA) physical status I - III
Exclusion criteria
Exclusion criteria: 1. Patients with a potentially difficult airway (Mallampati III or IV, thyromental distance of less than 6 cm, a limited mouth opening and/or cervical spine disease, Sleep apnea syndrome) 2. Patients who has reactive airway disease or signs of upper respiratory tract infection 3. Patients with risk of aspiration and regurgitation (e.g, pregnancy, hiatal hernia or GERD) 4.Patients with known allergies to study drugs (propofol, fentanyl) 5. Patients with body mass index <18 kg/m2 and > 30 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| required dose of propofol for effective LMA insertion with or without fentanyl use Immediately after LMA insertion attempt or Post-intervention mg of propofol administered until successful LMA insertion confirmed by chest rise or EtCO2 | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic stability Before and after LMA insertion Changes in BP and HR from baseline,Time to LMA insertion time since LMA insertion until EtCO2 present Seconds from propofal injection to successful LMA placement | — |
Countries
Thailand
Contacts
Public ContactWariya Sukhupragarn
Department of Anesthesiology,Faculty of Medicine, Chiang Mai University
Outcome results
None listed