breast cancer breast cancer, analgesic effect, pain, interpectoral plane block, deep serratus anterior plane block
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who plan to undergo unilateral major breast surgery (mastectomy, mastectomy with sentinel lymph node biopsy and modified radical mastectomy) 2. Age 20-75 years 3. ASA physical status 1-3 4. Reading ability is required
Exclusion criteria
Exclusion criteria: 1. Refuse to participate 2. Body weight lower than 35 kg 3. Allergy to study drugs; paracetamol, parecoxib, fentanyl, morphine, naproxen or bupivacaine 4. Contraindication to IPPB or SAPB include skin infection at block site or coagulopathy 5. Inability to cooperate, communication or report pain scores 6. Psychiatric disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative morphine consumption (milligrams) at 12 hours postoperatively IV patient-controlled analgesia (PCA) device | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative morphine consumption at PACU, 6, 24 and 48 hours IV PCA device,pain score at rest and movement at PACU, 6, 12, 24 and 48 hours postoperatively numeric rating scale,Opioid related-side effects such as PONV, sedation score and respiratory depression within 48 hours postoperatively interview,Length of hospital stay Patient will be discharged from hospital from IPD chart,quality of recovery at 24 hours postoperatively QoR-15,Patient satisfaction at 24 hours postoperatively questionnaire interview,First time to require rescue opioid At first tome to require rescue opioid IV PCA device | — |
Countries
Thailand
Contacts
Faculty of medicine, Khon Kaen University