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Comparison of the effects of intraoperative pectoral nerve block and local wound infiltration in the pain management for breast cancer surgery: A randomized controlled trial

Comparison of the effects of intraoperative pectoral nerve block and local wound infiltration in the pain management for breast cancer surgery: A randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250512009
Enrollment
22
Registered
2025-05-12
Start date
2023-03-13
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effective pain management strategies for patients diagnosed with breast cancer who have undergone a total mastectomy. breast cancer surgery pectoral nerve (PECS) block local infiltration post-operative pain local infiltration

Interventions

The surgeon performed PECS I, PECS II, and serratus plane blocks during surgery. The pharmacological agent utilized for this study was 0.5% bupivacaine, delivered in a volume of 20 ml, which had previ
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
The Pectoral nerve block (PECS) group ,Local infiltration group

Sponsors

Panyananthaphikkhu chonpratan medical center Ethics in Human Research
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: The study included participants aged 18 years or older, categorized as having physical status I-III, as defined by the American Society of Anaesthesiologists (ASA), who were scheduled to undergo elective mastectomy for breast cancer.

Exclusion criteria

Exclusion criteria: Exclusion criteria comprised individuals who did not provide written informed consent, exhibited ASA physical status IV or higher, had locally advanced breast malignancies with skin ulceration or infiltration of the chest wall, presented contraindications for peripheral nerve blocks or local anaesthetic infiltration (such as local infection or coagulopathy), possessed a history of allergic reactions to local anaesthetics, or were receiving treatment for psychiatric disorders.

Design outcomes

Primary

MeasureTime frame
The duration of analgesia the interval between extubation and the administration of the first rescue analgesia Patient reported outcome using a standard case record form ,The total cumulative dose of morphine required to maintain NRS scores below three during the first 24 hours post-surgery Patient reported outcome using a standard case record form

Secondary

MeasureTime frame
Evaluation of pain at post operative At 1, 6, 12 , 24 hours after surgey the standardized Numerical Rating Scale (NRS),Adverse effect Within 24 hours postoperation Patient reported outcome using a standard case record form

Countries

Thailand

Contacts

Public ContactPanutchaya Kongon

Panyananthaphikkhu Chonprathan Medical Center, Srinakharinwirot university

ghent_911@hotmail.com0818156908

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026