Effective pain management strategies for patients diagnosed with breast cancer who have undergone a total mastectomy. breast cancer surgery pectoral nerve (PECS) block local infiltration post-operative pain local infiltration
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The study included participants aged 18 years or older, categorized as having physical status I-III, as defined by the American Society of Anaesthesiologists (ASA), who were scheduled to undergo elective mastectomy for breast cancer.
Exclusion criteria
Exclusion criteria: Exclusion criteria comprised individuals who did not provide written informed consent, exhibited ASA physical status IV or higher, had locally advanced breast malignancies with skin ulceration or infiltration of the chest wall, presented contraindications for peripheral nerve blocks or local anaesthetic infiltration (such as local infection or coagulopathy), possessed a history of allergic reactions to local anaesthetics, or were receiving treatment for psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The duration of analgesia the interval between extubation and the administration of the first rescue analgesia Patient reported outcome using a standard case record form ,The total cumulative dose of morphine required to maintain NRS scores below three during the first 24 hours post-surgery Patient reported outcome using a standard case record form | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of pain at post operative At 1, 6, 12 , 24 hours after surgey the standardized Numerical Rating Scale (NRS),Adverse effect Within 24 hours postoperation Patient reported outcome using a standard case record form | — |
Countries
Thailand
Contacts
Panyananthaphikkhu Chonprathan Medical Center, Srinakharinwirot university