Prediabetic patients coenzyme Q10 coQ10 diabetes LDL oxidative stress oxidized LDL oxLDL ubiquinone
Conditions
Interventions
Daily ubiquinol with the dosage of 100 mg for 12 weeks A 500-mg soft gelatin capsule containing 100 mg of ubiquinol (Kaneka ubiquinolTM) emulsified with 400 mg of Medium Chain Triglycerides (MCT) oil
Experimental Dietary Supplement,Placebo Comparator Dietary Supplement
Sponsors
Anti-aging and Regenerative Medicine, College of Integrative Medicine, Dhurakij Pundit University, Bangkok, Thailand
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-60 years 2. Prediabetes defined as having fasting plasma glucose between 100 and 125 mg/dl
Exclusion criteria
Exclusion criteria: 1. Diagnosed of diabetes or use of oral hypoglycemic agents 2. Use of vitamins or other antioxidant supplements within the past 6 months 3. Uncontrolled hypertension 4. Diagnosed or previous history of cardiovascular disease 5. Renal insufficiency 6. Pregnancy or breast feeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference of serum oxidized low-density lipoprotein level between 2 groups at 12 weeks. 12 weeks Serum oxidized low-density lipoprotein | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in serum oxidized low-density lipoprotein level at 12 weeks compared to baseline. 12 weeks Serum oxidized low-density lipoprotein | — |
Countries
Thailand
Contacts
Public ContactRomun Leaovitavat
Anti-aging and Regenerative Medicine, College of Integrative Medicine, Dhurakij Pundit University
Outcome results
None listed