Accuracy and utility of 24-hour preoperative surgeon-performed ultrasound in head and neck squamous cell carcinoma neck dissection surgery

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250512006

Enrollment

Registered

2025-05-12

Start date

2025-08-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Level of cervical lymph node metastasis Head and neck squamous cell carcinoma HNSCC Squamous cell carcinoma of oral cavity SCCOC Selective neck dissection SND Supraomohyoid neck dissection SOHD Therapeutic neck dissection Ultrasound Preoperative ultrasound

Interventions

After inclusion each patient will undergo preoperative ultrasound examination within 24 h prior to surgery by an experienced head and neck surgeon with more than 10-year experience in head and neck su

Active Comparator Device

24-hour preoperative surgeon-performed ultrasound

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >18-year-old 2. Pathological diagnosis of HNSCC, including subsites of oral cavity, nasal cavity, nasopharynx, oropharynx, hypopharynx, larynx (Supraglottis, Glottis, Subglottis) and face 3. Admitted for neck dissection surgery of one or more neck node level from level Ia, Ib, II, III, IV, and V 4. Preoperative evaluation must include either CT or MRI of the associated region 5. No distant metastasis

Exclusion criteria

Exclusion criteria: 1. Previous head and neck irradiation or chemotherapy 2. Previous deep neck surgery on the ipsilateral side, defined as any neck surgery beyond subplatysmal plane 3. Any concurrent HNSCC 4. Contraindicated to surgical management making neck dissection surgery not possible in the admission or switch to palliative aimed treatment 5. Not willing to give informed consent

Design outcomes

Primary

Measure	Time frame
The sensitivity, specificity, positive predictive value, and negative predictive value of the 24-h preoperative surgeon-performed ultrasound within 24 h preoperative period Ultrasound nodal status	—

Secondary

Measure	Time frame
True positivity compared to preoperative computer tomography scan, Potential on guiding neck level selection, Incidence of occult and non-occult lymph node metastasis, Time from scan to operation within 24 h preoperative period Incidence	—

Countries

Thailand

Contacts

Public ContactItthiwat Oopachodsuwan

King Chulalongkorn memorial hospital

itthiwat.oop@chulahospital.org022564000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026