Acceptability and efficacy of coconut sugar-based oral rehydration solution (ORS) for management children with acute gastroenteritis

Acceptability and efficacy of coconut sugar-based oral rehydration solution (ORS) for management children with acute gastroenteritis : A randomized controlled trial

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250509004

Enrollment

Registered

2025-05-09

Start date

2024-12-11

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dehydration in pediatric acute gastroenteritis needs to be corrected with oral rehydration solution (ORS). Child, coconut, gastroenteritis, oral rehydration solution, taste

Interventions

A coconut sugar-based oral rehydration solution ORS will be prepared by the Nutrition Department of the HRH Princess Maha Chakri Sirindhorn Medical Center. The attending physicians will be blinded to

Experimental Drug,Active Comparator Drug

Coconut sugar-based oral rehydration solution ,Standard oral rehydration solution

Eligibility

Sex/Gender

All

Age

1 Months to 6 Years

Inclusion criteria

Inclusion criteria: Children admitted to the pediatric ward with acute diarrhea and mild to moderate dehydration.

Exclusion criteria

Exclusion criteria: (1) severe dehydration (2) evidence of severe systemic illness such as congenital heart disease, chronic pulmonary disease, liver or kidney disease, immunodeficiency and severe malnutrition (3) diagnosed or suspected surgical conditions such as appendicitis and gut obstruction (4) inability to tolerate oral intake (5) children aged 7 years or older

Design outcomes

Primary

Measure	Time frame
Acceptance of oral rehydration solution The first administration and repeated 24 hours after treatment initiation A researcher observation form, a five-point facial hedonic scale, a direct question on acceptability, a visual analogue scale.	—

Secondary

Measure	Time frame
Rehydration efficacy At 24 hours after the initiation of treatment Hydration status, Vital signs, Urine output, Lab investigation, Pre-discharge body weight,Length of diarrheal episode Until recovery from acute diarrhea or within a maximum of 7 days. Total number of hours,Duration of intravenous fluid administration Upon stopping the IV infusion Total number of hours,Total length of hospital stay No condition related to acute gastroenteritis Total number of hours,Total volume of ORS consumed At 4 hours and 24 hours after the initiation of treatment Total volume of ORS consumed (measured in mL) ,Occurence of adverse effect From enrollment to study completion Assessed by direct observation and caregiver report	—

Measure

Time frame

Rehydration efficacy At 24 hours after the initiation of treatment Hydration status, Vital signs, Urine output, Lab investigation, Pre-discharge body weight,Length of diarrheal episode Until recovery from acute diarrhea or within a maximum of 7 days. Total number of hours,Duration of intravenous fluid administration Upon stopping the IV infusion Total number of hours,Total length of hospital stay No condition related to acute gastroenteritis Total number of hours,Total volume of ORS consumed At 4 hours and 24 hours after the initiation of treatment Total volume of ORS consumed (measured in mL) ,Occurence of adverse effect From enrollment to study completion Assessed by direct observation and caregiver report

—

Countries

Thailand

Contacts

Public ContactSanguansak Rerksuppaphol

Faculty of Medicine, Srinakharinwirot University

sangunsak_r@hotmail.com0817231766

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026