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Incidence and Key Predictors of Microvascular Obstruction Through Cardiac Magnetic Resonance in Acute ST-Elevation Myocardial Infarction Patients

Incidence and Key Predictors of Microvascular Obstruction Through Cardiac Magnetic Resonance in Acute ST-Elevation Myocardial Infarction Patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20250506007
Enrollment
67
Registered
2025-05-06
Start date
2025-05-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ST-elevation myocardial infarction (STEMI) microvascular obstruction (MVO) ST Segment Elevation Myocardial Infarction cardiac magnetic resonance imaging microvascular obstruction

Interventions

Patients with acute coronary syndrome defined by persistent ST-segment elevation
Diagnostic
Group 1

Sponsors

Faculty of Medicine, Chiang Mai University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 20 2. Patients with acute coronary syndrome defined by persistent ST-segment elevation or new-onset left bundle branch block (LBBB) on a 12-lead ECG 3. Patients who were scheduled for PPCI within 12 hours of symptom onset. 4. Evidence of impaired coronary blood flow or coronary artery stenosis/obstruction as identified through coronary angiography (>50% stenosis at culprit artery by visual estimation or software-based technique Quantitative coronary angiography (QCA)) 5. Patients who are indicated for cardiac magnetic resonance imaging for further evaluation, as determined by the responsible physician

Exclusion criteria

Exclusion criteria: 1. Contraindications for MRI: Claustrophobia, pregnancy, estimated glomerular filtration rate eGFR less than 30 mL/min/1.73 mx2, and the presence of certain medical devices, such as cerebral, carotid, or aortic aneurysm clips, deep brain stimulators, and cochlear implants. 2. Inability to provide informed consent

Design outcomes

Primary

MeasureTime frame
incidence of microvascular obstruction 2 - 7 days Events

Secondary

MeasureTime frame
independent risk factors 2 - 7 days Risk Factors

Countries

Thailand

Contacts

Public ContactJakkapun Yanyongmathe

Faculty of Medicine, Chiang Mai University

palmjakkapun@gmail.com6653936793

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026