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Biotin and hair loss

Is the addition of Oral Biotin in PRP more beneficial for treating male pattrten hair loss compared to PRp alone?A randamized controlo trial.

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250506001
Enrollment
180
Registered
2025-05-06
Start date
2024-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

androgenic alopecia Androgenic Alopecia, Biotin, PRP,

Interventions

Group A consisting of 90 patients received 4 sessions of Platelets rich plasma,1 month apart while Group B were treated with similar protocol of Platelets Rich Plasma therapy in combination with oral
Active Comparator Drug,Active Comparator Drug
Platelets Rich Plasma ,Platelets Rich Plasma wih oral biotin

Sponsors

Tehsil headquarters hospital,Takhtbhai,mardan,KPK,Pakistan
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1.All male patients with hair loss (Hamilton score II-V), 2. between age 18-50 years, 3.willing to give written consent for the procedure and come for monthly follow-up were included in this study

Exclusion criteria

Exclusion criteria: 1. All condition contributing to hail loss such as thyroid abnormalities, anemia, connective tissue dis-eases and malnutrition etc. 2.History of scalp surgery and the use of drugs such as minoxidil or antiandrogens in past 6 months 3. patients with major organ failure such as cardiovascu-lar, renal or hepatic were considered ineligible. 4.Similarly, patients with Thrombocytopenia (low platelet count), hemodynamic instability (low BP, collapse), HBV/HCV infection and other condi-tions predisposing to excessive bleeding as well as local scalp infections 5. history of allergy to previous session of PRP were excluded.

Design outcomes

Primary

MeasureTime frame
Hair density improvment 6 months digitla photography

Secondary

MeasureTime frame
dermatology quality of life index 6 months standred scale

Countries

Pakistan

Contacts

Public ContactMuhammad Fahim

Tehsil headquarters hospital Takhtbhai

clinicaldermatologist@gmail.com03465354921

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026