Patients with keloid scar Keloid Steroid Platelet rich plasma PRP
Conditions
Interventions
Intra-operative corticosteroid injection alone was administered around the surgical wound using triamcinolone acetonide (40 mg/ml). The injection was performed into the intradermal layer using a 30G n
Active Comparator Drug,Experimental Drug
Intra-operative corticosteroid injection,Combined Intra-operative platelet-rich plasma with corticosteroid injection
Sponsors
Chanokchon Kongkergkiat, M.D.
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or older 2. Having keloid scars less than 10 centimeters in length 3. Undergoing complete keloid excision (extralesional excision) 4. Undergoing surgery under local anesthesia
Exclusion criteria
Exclusion criteria: 1. Patients currently receiving immunosuppressive drugs or systemic steroids 2. Patients with chronic diseases under active treatment, such as tuberculosis 3. Pregnant or breastfeeding women 4. Patients likely to have poor treatment adherence, such as those with cancer, epilepsy, or psychiatric disorders 5. Patients with vascular diseases or hematologic/coagulation abnormalities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate of keloid Within 12 months after end of the intervention Vancouver scar scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Itching at scar Within 12 months after end of the intervention Patient reported outcome using a questionnaire interview,Pain at scar Within 12 months after end of the intervention Patient reported outcome using a questionnaire interview,Skin atrophy Within 12 months after end of the intervention Clinical examination,Skin telangiectasia Within 12 months after end of the intervention Clinical examination | — |
Countries
Thailand
Contacts
Public ContactChanokchon Kongkergkiat
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed