Maternal hypotension (low blood pressure in pregnant women) occurring during spinal anesthesia for cesarean section in non-obese pregnant women, maternal hypertension, nausea and vomiting, neonatal APGAR score Ondansetron, Maternal hypotension, Spinal hypotension, Cesarean Section, nausea and vomiting
Conditions
Interventions
Ondansetron 4mg intravenous injection 10 minutes before spinal anesthesia
Experimental Drug
Sponsors
None listed
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Non-obese (BMI<30) Pregnant women undergoing cesarean section, 2. ASA (American Society of Anesthesiologists) physical status classification II or III. 3. Age more than 18 years, 4.Term pregnancy (gestational age more than 37 weeks)
Exclusion criteria
Exclusion criteria: 1.Received ondansetron less than 10 minutes before spinal anesthesia. 2.Cerebrovascular disease. 3.Obstetric complications (placental abruption, placenta previa). 4.Fetal abnormality diagnosed antenatally. 5.History of monoamine oxidase inhibitor (MAOI) use or medications that slow cardiac conduction. 6.Received other intravenous sedatives besides ondansetron, spinal anesthesia, and spinal morphine before delivery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spinal hypotension From spinal anesthesia to baby delivery Blood pressure measurement in units of millimeters of mercury (mmHg) | — |
Secondary
| Measure | Time frame |
|---|---|
| Vasopressor Consumption From spinal anesthesia to baby delivery mcg of phenylephrine administration,nausea and vomiting From spinal anesthesia to baby delivery numbers of episodes and scores | — |
Countries
Thailand
Contacts
Public ContactMarshima Chaosaowapa
Chaophrayayommaraj Hospital
Outcome results
None listed