Maternal hypotension (low blood pressure in pregnant women) occurring during spinal anesthesia for cesarean section in obese pregnant women. Ondansetron, Maternal hypotension, Spinal hypotension, Maternal obesity, Cesarean Section
Conditions
Interventions
Ondansetron 4mg intravenous injection 10 minutes before spinal anesthesia,Ondansetron 6mg intravenous injection 10 minutes before spinal anesthesia,Ondansetron 8mg intravenous injection 10 minutes bef
Experimental Drug,Experimental Drug,Experimental Drug
Ondansetron 4mg ,Ondansetron 6mg ,Ondansetron 8mg
Sponsors
Chaophrayayommarat Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Pregnant women with obesity undergoing cesarean section, 2. ASA (American Society of Anesthesiologists) physical status classification II or III. 3. Age more than 18 years, 4.Term pregnancy (gestational age more than 37 weeks)
Exclusion criteria
Exclusion criteria: 1.Received ondansetron less than 10 minutes before spinal anesthesia, 2.History of cerebrovascular disease, 3.Obstetric complications, such as: Placental abruption, Placenta previa, Fetal abnormalities detected during pregnancy, 4.History of using: Monoamine oxidase inhibitors (MAOIs), Drugs that slow cardiac conduction, 5.Received other intravenous anesthetic drugs (excluding ondansetron, spinal anesthetics, and intrathecal morphine) before delivery of the baby.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spinal hypotension From spinal anesthesia to baby delivery Blood pressure measurement in units of millimeters of mercury (mmHg) | — |
Secondary
| Measure | Time frame |
|---|---|
| Vasopressor Consumption From spinal anesthesia to baby delivery Dose of phenylephrine(microgram) or atropine(milligram) intravenous injection as indicated | — |
Countries
Thailand
Contacts
Public ContactOrnphimon Tanaphuwanont
Chaoprayayommarat hospital
Outcome results
None listed