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Thyrotoxic Hypokalemic Periodic Paralysis: A Case Series from two Tertiary Medical Centers in Thailand

The clinical characteristics of thyrotoxic periodic paralysis patients in Thai Red Cross Society Hospitals

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20250427002
Enrollment
30
Registered
2025-04-27
Start date
2014-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thyrotoxic periodic paralysis thyrotoxicosis

Interventions

the patients with thyrotoxic periodic paralysis are the patients presenting with Transient paralytic attack observed by a physician with Hypokalemia during the paralytic attacks with hyperthyroidism c
Supportive Care
thyrotoxic periodic paralysis

Sponsors

Faculty of Medicine, Chulalongkorn University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. All Thai patients presenting with Thyrotoxic periodic paralysis by the definition of transient paralytic attack observed by a physician with Hypokalemia during the paralytic attacks with (serum potassium level: <3.5 mmol/l) and presence of hyperthyroidism confirmed by thyroid function tests from King Chulalongkorn Memorial Hospital and Queen Savang Vadhana Memorial Hospital (Thai Red Cross society hospitals) in 5 year period

Exclusion criteria

Exclusion criteria: 1. Patients who already had a neurological deficit before the attack 2. Patients who took diuretics for the treatment of other medical diseases 3. Patients who were referred from other hospitals after medical treatment 4. Patients who had impaired renal function (GFR < 60 ml/min/1.73 m2) were also excluded.

Design outcomes

Primary

MeasureTime frame
Clinical characteristics of thyrotoxic periodic paralysis : muscle involved, severity of muscle weakness by MRC scales, time of the attack, recovery time, symptoms and signs of hyperthyroidism at the end of 2018 descriptive statistics

Secondary

MeasureTime frame
baseline characteristics: age gender, geographic residence region at the end of 2018 descriptive statistics,complication of thyrotoxic periodic paralysis: respiratory failure, arrhythmia, rebound hyperkalemia at the end of 2018 descriptive statisics

Countries

Thailand

Contacts

Public ContactSutharn Suteetorn

Thai Red Cross Society Hospital

tk_kyori@hotmail.com022564000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026