Female patients aged 18-70 years undergoing elective mastectomy with or without axillary lymph node dissection Mastectomy, Breast Neoplasms, Elective Surgical Procedures
Conditions
Interventions
An ESPB was performed at the level of the T4 transverse process, and 30 mL of 0.33 percent bupivacaine with adrenaline (1:200,000) was injected. Non-penetrating needle contact was then performed at th
Experimental Procedure/Surgery,Experimental Procedure/Surgery
Single-level ESPB,Bi-level ESPB
Sponsors
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Female patients aged between 18-70 years 2. Patients with an American Society of Anesthesiologists (ASA) physical status I-III 1. Patients scheduled for an elective unilateral mastectomy with or without axillary lymph node dissection (ALND) 2. Patients who have provided written informed consent to participate in the study
Exclusion criteria
Exclusion criteria: 1. Patients with abnormal coagulation profiles 2. Patients with known allergies to any of the study drugs 3. Patients with a skin infection at the needle puncture sites 4. Patients who are unable to understand or use the numeric pain rating scale or patient-controlled analgesia (PCA) pump 5. Morbidly obese patients (BMI is greater than or equal to 40 kg/m2) 6. Patients with body weight less than 50 kg 7. Patients with severe liver dysfunction (Child-Pugh score > 9) Patients with a history of chronic opioid use
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour postoperative morphine consumption within 24 hours total morphine consumption within 24-hour postoperative | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain scores within 24 hours Numeric rating scale (NRS) pain scores at rest, ranging from 0 (no pain) to 10 (worst imaginable pain), recorded in the PACU and at 6, 12 and 24 hours postoperatively.,Incidences of nausea and vomiting during the 24-hour postoperative period within 24 hours Patient reported outcome | — |
Countries
Thailand
Contacts
Public ContactNolchanok Eamjitmetta
Department of Anesthesiology Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed