Robotic-assisted radical laparoscopic prostatectomy is a minimally invasive procedure commonly used to treat prostate cancer. In recent years, the use of robotic-assisted radical prostatectomy (RARP) has significantly increased due to its numerous benefits, including smaller incisions, improved postoperative urinary continence, and reduced need for blood transfusions. However, despite these advantages, patients often experience significant immediate postoperative pain, largely attributed to int
Conditions
Interventions
A bolus of lidocaine 1.5 mg/kg of ideal body weight or an equivalent volume of normal saline (NSS) is administered by the anesthetist during anesthetic drug induction. The intravenous infusion of lido
Experimental Drug,No Intervention Drug
Intraoperative lidocaine infusion,NSS infusion
Sponsors
Faculty of Medicine, Prince of Songkla University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: - Patients scheduled for elective robotic-assisted radical prostatectomy (RARP) - ASA classification I-III - Able to communicate and rate pain score as Verbal Numeric Rating Scale (VNRS) - Able to use intravenous patient-controlled analgesia (IV PCA)
Exclusion criteria
Exclusion criteria: - Known allergy to lidocaine or other amide local anesthetics - History of chronic pain requiring regular opioid or analgesic use within the past 3 months - Severe liver or renal disease CKD stage 4-5, Child-Pugh Class C, acute liver failure - Hypothyroidism - History of heart block, preexisting hypotension, or severe bradycardia with heart rate below 50 bpm - BMI exceeding 40 kg/m2 - History of Adam-Stoke Syndrome, Wolff-Parkinson-White Syndrome, Parkinson disease - Currently using specific medication, such as phenytoin, procainamide, tocainide,quinidine, beta-blocking agents, cimetidine - Family history of malignant hyperthermia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pain 0, 1, 2, 4, 12, 18 and 24 hours postoperatively Verbal numerical rating scale | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative fentanyl consumption 0, 1, 2, 4, 12, 18 and 24 hours postoperatively total fentanyl consumption,quality of recovery 24-48 hours postoperatively QoR-15 questionnaire,total length of hospital stay 1-2 weeks postoperatively total length of hospital stay (days) | — |
Countries
Thailand
Contacts
Public ContactRatikorn Boonchai
Prince of Songkla University
Outcome results
None listed